This course will provide an overview of different research areas in the field of functional DNA nanotechnology and their intersections with the fields of genomics, biophysics, and healthcare. The course is organized into four modules: i) DNA in The Post-Genomics Era, ii) Nucleic Acids as Enzymes and Binders, iii) Molecular Programming with DNA, and iv) Structural DNA nanotechnology. Through these modules, students will familiarize with different biophysical and biochemical properties of our genetic material. Evaluations will be based on in-class participation, paper presentations, reports, and drafting of a mock grant.