Critical appraisal is an important responsibility of all public health leaders and health care professionals undertaking research or evidence-informed practice. This course will focus on learning how to assess evidence. This course will also help students develop the ability to critically and effectively synthesize findings to generate evidence-informed practice that advances programs, policies, services and/or systems. The course will help students distinguish the different types of evidence and how they can be summarized. The methods, reporting, and critical appraisal of different types of knowledge synthesis that are often used in public health decision-making will be explored (e.g., scoping reviews, rapid reviews, overviews, network meta-analysis). Through developing a knowledge synthesis question, students will explore a broad range of disciplines and health related data sources, learn how to formulate critical questions, and will gain practice with developing a knowledge synthesis protocol.