The notion of a sensor device is common knowledge to all. The range of these structures in modern times is immense, ranging from simple physical measurements such as temperature to complex devices that incorporate human cells in their design. The number of applications is also numerous including industrial processing, pharmaceutical analysis, automotive operation, military technology, and environmental signalling to name just a few areas of use. In this course, we introduce the basics of a special branch of sensor technology that deals with the detection of chemicals and biological species, the chemical and biosensor device. The course proceeds from a description of overall sensor architecture, to devices types based on electrochemistry, piezoelectric acoustic wave physics and optical science. The course also covers potential applications of these devices especially in the world of medicine. The course is especially interdisciplinary in nature, allowing the student to gain a good understanding of the merging of chemistry with biology, materials science, and electronic engineering.