This course is unique in the Chemistry canon in that it provides practical background useful for understanding, repairing, and building simple (and not-so-simple) instrumentation that is ubiquitous in the modern analytical laboratory. On the subject of electronics, the course covers voltage and current, resistors, capacitors, inductors, diodes, transistors, op-amps, digital electronics, and microprocessors. On the subject of computer programming, the course covers an introduction to programming, algorithms, syntax, variables, functions, hardware control, and data processing and visualization. Finally, on the subject of optics, the course covers light sources, wavelength selectors, detectors, lenses, mirrors, prisms, polarizing optics, microscopy, and non-linear optics. The course includes a series of unique laboratory exercises to give you an opportunity to gain experience with the concepts and subjects discussed in the lectures.