The objective of the course is to introduce seismic assessment methods for structures through inelastic analyses or advanced experimental simulations. The course mainly consists of three sections: deterministic analytical assessment, reliability-based analytical assessment, and advanced experimental methods. In the first section, numerical models of inelastic structural and geotechnical materials, and various finite element models will be introduced. Built upon these topics, several seismic demand and capacity assessment methods will be presented. Analysis methods for soil-structure-interaction system will be also discussed in this section. In the second section, the fundamentals in structural reliability analysis will be briefly reviewed, which will be followed by a seismic fragility assessment. In the third section, the latest development in advanced experimental methods (experiment-analysis hybrid simulation) will be introduced. While the topics of this course will be presented from a perspective of seismic engineering, the knowledge gained from this course could be applied to research and practice in other areas of structural engineering.