Ultrasound is a high-resolution and rapid imaging modality that applies high frequency acoustic waves to create images based on echoes that are generated by acoustic impedance heterogeneity between different materials in a sample. Ultrasound imaging has many clinical applications from monitoring fetus in pregnancy, to diagnostic imaging of breast, abdomen, and vasculature, and guiding interventional tools in minimally-invasive procedures. This course will introduce the principles of ultrasound imaging, starting with a general overview of this imaging modality and its applications. It will cover ultrasound beam profiles and the basic physics of ultrasound, interaction of ultrasound waves with tissue transducers, signal processing and image formation and beam forming, transducer design, flow detection, contrast imaging, and assorted topics.