This course will present the fundamentals and applications of biosensors realized on microfluidic platforms. Topics to be covered include: Microfabrication techniques for constructing silicon, glass, and polymer devices; Microfluidic principles; Biosensing mechanisms; Design and analysis of microfluidic biosensors; Microfluidic immunosensors; Microfluidic nucleic acid sensors; Microfluidic chemical sensors; Other applications of microfluidic biosensors.