The purpose of this course is to provide students with an overview of the role of nutrition in the etiology of cancer development. Introductory lectures will provide a background to the scientific principles of cancer development (i.e., mechanisms of carcinogenesis, pathology) as well as an overview of study designs for conducting research programs of diet and cancer (i.e., animal models, epidemiologic studies, use of biomarkers). This will be followed by a series of lectures and discussion sessions on the role that foods and specific components of foods play in the development and progression of cancer at specific sites, including the colon, breast, and prostate. There will also be a chance for the graduate students to present the background of their proposed grant topic and to receive feedback from the group. The course will conclude with lectures on epigenetics and conducting studies of diet and cancer in high-risk populations.