PCL3115H: The DNA Damage Response in Pharmacology and Toxicology

Students will learn different internal and external sources that cause DNA damage; how DNA damage is detected and repaired; how DNA damage can trigger cell cycle arrest and cell death; how DNA damage factors into response of living organisms to various xenobiotics and antineoplastics.

Many anticancer drugs and environmental agents exert their cytotoxic effects through DNA damage. This course explores specific pharmacological and toxicological agents that damage DNA and examines how mammalian cells respond to this DNA damage.

Credit Value (FCE)

0.25

Exclusions

PCL477H1

Campus(es)

St. George

Delivery Mode

In Class

School of Graduate Studies University of Toronto 63 St. George Street Toronto, ON Canada M5S 2Z9
Tel: 416-978-6614

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We wish to acknowledge this land on which the University of Toronto operates. For thousands of years it has been the traditional land of the Huron-Wendat, the Seneca, and the Mississaugas of the Credit. Today, this meeting place is still the home to many Indigenous people from across Turtle Island and we are grateful to have the opportunity to work on this land.