This 9-week course will build on foundational knowledge and skills developed in previous courses and provide students with the opportunity to integrate principles of cardiovascular and respiratory anatomy and physiology, exercise physiology, clinical pathobiology, and dysfunction into the assessment and treatment of clients with cardiovascular, respiratory, and multi-morbidity conditions. The content presented in this course is critical to the holistic and comprehensive management of all clients. This course will continue to foster critical thinking, an inquiry mindset, and professionalism and students will be expected to integrate the essential physical therapy competencies throughout (i.e., physiotherapy expertise, communication, collaboration, management, leadership, scholarship, and professionalism).