This unique course involves a weekly two-hour lecture and a practicum component of four hours per week. Lectures focus on design issues in term one and analysis issues in term two. The practicum involves delving into one or more projects under the direct supervision of a Division of Biostatistics faculty-appointed biostatistician. Emphasis is placed on the analysis of data and interpretation of results. Student evaluation is based on end-of-term presentations, progress in the practicum component, and an end-of-year final report.