This course consists of two parts: A) Transition Metal Catalysis, and B) Reactive Intermediates. In the first part of the course, Prof. Rousseaux will discuss transition metal-catalyzed transformations for carbon-carbon bond formation. Aspects of reaction development, catalyst design and mechanistic information will be discussed. Selected topics (tentative) will include i) basic concepts in transition metal catalysis, ii) palladium-catalyzed cross-couplings and modern developments in this area, iii) C-H bond functionalization reactions, iv) Heck reactions, v) alkyl cross-couplings, and vi) sustainability in transition metal catalysis. The second part of the course will outline various aspects of the chemistry of reactive intermediates, including radicals, cations, carbenes, nitrenes, ketenes, and benzynes.