The course is organized as a series of clinical-pathological conferences and covers all forms of disease of the mouth. A case-based approach is used for teaching and learning. The material for study is derived from the Oral Pathology Diagnostic Service and the hospital pathology departments. Emphasis is placed on synthesizing clinical, radiographic and histological data for a comprehensive evaluation of the case being discussed. Current cases of interest are studied and in addition the surgical pathology of all oral disease is covered in a systematic manner. Seminars are held weekly during the Fall and Winter semesters. This course builds on the prerequisite course DEN1311Y Oral Surgical Pathology. Students will analyze more challenging cases of oral surgical pathology. They are expected to provide a wider scope of differential diagnosis that include less common diseases to account for clinical and/or radiographic findings, and recognize more complex histologic findings to arrive at a diagnosis. There is opportunity to address controversial aspects of management of the disease being considered and development of a treatment plan that follows the principles of patient-centered care.