This seminar introduces graduate students to the role of postcolonial theory in generating a "global turn" in histories of science and the multidisciplinary field of science & technology studies (STS). We will read and discuss how postcolonial scholars have critiqued historical and social studies of science, and debate the theoretical and methodological significance of ideas like "global perspectives," the "Global South," and "non-Western science" in STS. To evaluate the impact of these ideas on the field, we will also read recently published case studies applying postcolonial approaches to histories of science, technology, and medicine. Students will have the opportunity to compare these approaches with the related but distinct concepts of decoloniality emerging from Indigenous studies, and to consider how postcolonial STS can inform their own ongoing research.