PCL3116H: Endocrine Disruptors

The first part of the course would cover basics concepts and mechanisms of hormonal production, regulation of major endocrine glands, and discuss the etiopathology and clinical manifestations of some endocrine disorders.

The second part of the course would focus on the sources and pathways of exposure to various endocrine disrupting substances, as well as the various mechanisms of action of endocrine disruptors (e.g., alteration of hormone receptors, enzyme stimulation or inhibition, alteration in co-activators, etc).

The last part of the course would be an endocrine disrupting seminar, during which each student presents the objectives, methods, and main findings of a peer-reviewed publication investigating the endocrine disrupting effects of one or multiple environmental contaminants. The students will also be invited to critique the paper and propose a follow-up research project.

0.25
St. George
In Class