A lecture course with assigned reading which will focus on the fundamental biology of microbial biofilms and how biofilm ecology impacts on the pathogenesis of infections. The course draws knowledge of oral microbiology, microbial genetics, and functional genomics. It is intended as a core course for graduate students whose specialty areas deal with biofilm-related diseases and for doctoral stream students from diverse SGS departments, whose research centers on bacterial adhesion, bacterial physiology, and bacterial genetics. Evaluation will consist of reading quizzes and one written term exam at the end of the course.