Ruminations about causality are at the center of our very idea of a science. This course will explore various developments associated with the scientific revolution (understood in the broader sense to signify the rejection of the Aristotelian worldview and its replacement by the mechanistic cosmos associated with Galileo, Descartes, and Newton) from the point of view of the notion of causation (a subsidiary goal will be the use the scientific revolution as a background for helping us get clear on the notion of causality). Starting with a discussion of Aristotle's theory of causation as elaborated both in his work as philosopher and as naturalist, we will then turn to developments in astronomy and cosmology, mechanics, natural history, biology, geology, and chemistry, exploring the sense, if any, in which these developments involved a rejection of Aristotle's theory(s) of causation. The course will be conducted as a seminar, with students selecting topics for presentation at our first meeting.