Pharmacokinetics (PK) describes "what the body does to the drug" and links the drug's dose to its exposure. Understanding the PK properties of a drug is important along the entire life cycle of the drug, from early drug development to its real-world applications in precision medicine.

This course begins with a basic understanding to the core principles and concepts of PK. Next, the course will introduce two PK modelling approaches, population PK (PopPK) and physiologically based PK (PBPK) models, as key applications of PK. Using the newly attained PK knowledge, students will learn to create PopPK and PBPK models with PhoenixTM NLME and PK-Sim, respectively. Students will learn about the applications of these models, including identifying a starting dose, comparing formulations, scaling between species (e.g., mice to humans), evaluating associations between clinical factors and PK parameters, and designing experiments, to name a few.

The course concludes with an invited panel of PK professionals to allow students the opportunity to ask questions and gain insight into potential careers. Overall, the course offers students a rarity of skills in PK that can be applied to multiple fields and career paths in pharmaceutical sciences.