We study how climate changes (heat, sea levels, precipitation) affect human activity and welfare (agriculture, housing, infrastructure, health), when meditated by adaptation (migration, asset markets, trade) and other considerations (heterogeneity, space, frictions, expectations, uncertainty), in equilibrium. We introduce frontier structural modeling methods. These provide theoretical insights and, together with data, quantitative welfare and policy analysis. In a final project, students apply appropriate methods to a question of their choice.