This course consists of lectures, discussion, and student-led seminars designed to be highly engaging, dynamic, and likely different each time it runs. This is where students can expect to be exposed to the bleeding edge of the field of genomic medicine and where they will position themselves at the vanguard of the field. They will learn about cutting-edge technologies that may or may not yet have reached the clinic directly from the experts researching, developing, and using them. This seminar class will provide a survey of topics and is rooted in a journal-club style of discursive learning. It will include primarily the assessment of individual work.