This is a series of seminars and ward rounds directed by the Department of Pediatrics at the Hospital for Sick Children. A study of growth and development from birth to adulthood is presented, stressing normal values as well as causes and effects of deviations from them. This course runs concurrently with DEN4010Y and major topic areas are reinforced through patient presentations during ward rounds. Major infections are reviewed as to etiology, clinical manifestations and treatment, and current immunization procedures are presented. Tumors of a benign or malignant nature which are common to the pediatric age group are discussed as to clinical aspects and current therapies, and common bleeding disorders are described, with emphasis on management and relevance to dental practice. The aspects of cardiac disease in childhood are presented as well as related prophylactic measures in current use in dental practice. A lecture on basic genetics is given as to modes of inheritance, chromosomal abnormalities, and methods of investigation. At the Hospital for Sick Children, patients are presented who represent some of the subjects discussed in the lecture series, thereby enhancing the latter through clinical illustrations.