Biochemistry

Biochemistry: Introduction

Faculty Affiliation

Medicine

Degree Programs

Biochemistry

MSc and PhD

Combined Degree Programs

MD / PhD

Collaborative Specializations

The following collaborative specializations are available to students in participating degree programs as listed below:

Overview

Biochemistry is the study of the molecular events underlying biological processes. Consequently, it makes fundamental contributions to all disciplines concerned with living systems.

The Department of Biochemistry offers modern facilities for research in a wide variety of areas including the relationship between structure and biological function in proteins, nucleic acids, and lipids as well as complex multicomponent systems such as membranes and subcellular organelles.

Contact and Address

Web: biochemistry.utoronto.ca
Email: carrie.harber@utoronto.ca
Telephone: (416) 978-4815
Fax: (416) 946-8228

Department of Biochemistry
University of Toronto
Room 5207, Medical Sciences Building
Toronto, Ontario M5S 1A8
Canada

Biochemistry: Graduate Faculty

Full Members

Adeli, Khosrow - DipChem, MSc, PhD
Andrews, David - PhD
Angers, Stéphane - BSc, PhD
Attisano, Liliana - BSc, PhD
Bear, Christine - BSc, MSc, PhD
Brown, Grant - BSc, PhD
Chakrabartty, Avijit - BSc, MSc, PhD
Chan, Hue Sun - BSc, MA, PhD
Davidson, Alan Richard - BSc, PhD
Deber, Charles - BSc, PhD
Ensminger, Alexander - BS, PhD
Ernst, Oliver - PhD
Forman-Kay, Julie - BSc, PhD
Glover, John - BSc, MSc, PhD
Grinstein, Sergio - BSc, PhD
Harrington, Lea Anne - BSc, MSc, PhD (Chair and Graduate Chair)
Houry, Walid - BS, MS, PhD
Howell, Lynne - BSc, PhD
Julien, Jean-Philippe - PhD
Kay, Lewis - PhD
Keeley, Frederick - BSc, PhD
Kelley, Shana - BA, PhD
Kim, Peter - PhD
Klip, Amira - ScD
Lee, Hyun - PhD
Lee, Warren - MD, PhD
Maxwell, Karen - PhD
Maynes, Jason T. - BSc, DrMed
McQuibban, Angus - BSc, MSc, PhD
Melnyk, Roman - PhD
Moraes, Trevor - BS, MSc, PhD (Graduate Coordinator)
Muise, Aleixo - MD
Nodwell, Justin - PhD
Ohh, Michael - BSc, PhD
Palazzo, Alexander - PhD
Parkinson, John - BS, PhD
Pomes, Regis - PhD
Prive, Gil - BSc, PhD
Rand, Margaret - BSc, PhD
Reithmeier, Reinhart - BSc, PhD
Rini, James - BSc, PhD
Rotin, Daniela - BSc, MSc, PhD
Rubinstein, John - BSc, PhD, PhD
Schulze, Andreas - MD
Schuurmans, Carol - PhD
Sharpe, Simon J. - BSc, PhD
Sicheri, Frank - BSc, PhD
Smibert, Craig - BSc, PhD
Stagljar, Igor - BS, PhD
Steipe, Boris - MD, PhD
Trimble, William - BSc, PhD
Yip, Christopher - BSc, PhD

Members Emeriti

Anwar, Rashid - BSc, MSc, PhD
Baker, Robert - BSc, PhD
Gurd, James - BA, PhD
Isenman, David - BSc, BSc, PhD
Lane, Byron - BA, PhD
Lewis, Peter - BSc, PhD
Lingwood, Clifford - BSc, PhD
Marks, Alexander - MD, PhD
Moran, Laurence - BSc, PhD
Murray, Robert - MS, MD, MB, PhD
Pai, Emil - PhD
Painter, Robert - BSc, PhD
Robinson, Brian - BSc, PhD
Sarkar, Bibudhendra - BPhm, MPharm, PhD
Schachter, Harry - BA, MD, PhD
Segall, Jacqueline - BSc, PhD
Williams, David - BSc, MSc, PhD
Williams, George - BSc, DSc, DSc, FRSC

Associate Members

Andreopoulos, Stavroula - BSc, MSc, PhD
Lee, Nana Hyung-Ran - PhD
Norris, Michael - PhD
Patterson, Sian - PhD

Biochemistry: Biochemistry MSc

Students may begin the Master of Science (MSc) program in the Fall or Winter.

MSc Program

Minimum Admission Requirements

  • Applicants are admitted under the General Regulations of the School of Graduate Studies. Applicants must also satisfy the Department of Biochemistry's additional admission requirements stated below.

  • Normally, a minimum B+ average in the last two years of study in an honours or specialist BSc program in biochemistry or molecular biology. Applicants with strong academic credentials in honours or specialist programs in disciplines related to biochemistry or molecular biology are also considered.

  • Applicants arrange for personal reference forms from three individuals familiar with their academic performance.

  • Applicants who obtained a degree outside Canada or the United States are generally required to have an MSc degree in Biochemistry or in a closely related subject area.

  • Applicants whose primary language is not English and who graduated from a non-Canadian university where the language of instruction was not English must provide Test of English as a Foreign Language (TOEFL) and Test of Written English (TWE) scores:

    • paper-based TOEFL: minimum 580 score and 5 on the TWE

    • Internet-based TOEFL: minimum 93/120 score and 22/30 on the writing and speaking sections.

  • In the absence of TOEFL results, an International English Language Testing System (IELTS) score of at least 7.0 (Academic) with at least 6.5 for each component is also acceptable.

Completion Requirements

Students must complete any courses that were a condition of acceptance.

  • Coursework. Students must successfully complete a total of 1.5 full-course equivalents (FCEs) as follows:

    • BCH2020Y Seminar Course in Biochemistry Level 1

    • BCH2101H Scientific Skills for Biochemists

    • at least 0.25 elective FCE

  • Students must submit a thesis and successfully complete an oral examination on their research and related aspects of biochemistry.

  • Normally, MSc students are expected to participate as full-time students and to maintain full-time status in their laboratories until thesis completion and final defence.

Mode of Delivery: In person
Program Length: 6 sessions full-time (typical registration sequence: FWS-FWS)
Time Limit: 3 years full-time

 

Biochemistry: Biochemistry PhD

Students are accepted into the Doctor of Philosophy (PhD) program via one of three routes: 1) following completion of an MSc degree in biochemistry or a cognate discipline; 2) transfer (reclassification) from the University of Toronto MSc program; or 3) following completion of a BSc degree (direct entry) if, in the opinion of the Biochemistry Graduate Committee, the student has an outstanding academic record.

PhD Program

Minimum Admission Requirements

  • Applicants are admitted under the General Regulations of the School of Graduate Studies. Applicants must also satisfy the Department of Biochemistry's additional admission requirements stated below.

  • Applicants must arrange for personal reference forms from three individuals familiar with their academic performance.

  • Applicants are generally required to have an MSc degree in biochemistry or in a closely related subject area with high academic standing.

  • Applicants whose primary language is not English and who graduated from a non-Canadian university where the language of instruction was not English must provide Test of English as a Foreign Language (TOEFL) and Test of Written English (TWE) scores:

    • paper-based TOEFL: minimum 580 score and 5 on the TWE

    • Internet-based TOEFL: minimum 93/120 score and 22/30 on the writing and speaking sections.

  • In the absence of TOEFL results, an International English Language Testing System (IELTS) score of at least 7.0 (Academic) with at least 6.5 for each component is also acceptable.

Completion Requirements

Students must complete any courses that were a condition of acceptance.

  • Coursework. Students must successfully complete a total of 2.0 full-course equivalents (FCEs) as follows:

    • BCH2022Y Seminar Course in Biochemistry Level 2

    • BCH2101H Scientific Skills for Biochemists. If previously taken students must take a substitute 0.25 FCE course approved by the graduate coordinator.

    • 0.75 elective FCE

  • Students must successfully complete a qualifying examination within the first 24 months (ideally 18 months) of the program. To be eligible to write this qualifying examination, students must:

    • complete BCH2101H

    • be concurrently registered in BCH2022Y

    • complete at least 0.25 elective FCE; after completing the qualifying examination, students must complete the remaining 0.5 elective FCE.

  • Submit a thesis and defend it at the Doctoral Final Oral Examination.

  • Normally, PhD students are expected to participate as full-time students and to maintain full-time status in their laboratories until thesis completion and final defence.

Mode of Delivery: In person
Program Length: 4 years full-time (typical registration sequence: Continuous)
Time Limit: 6 years full-time

 

PhD Program (Transfer)

Transfer Requirements

  • Transfer applicants must be enrolled in the MSc program in Biochemistry. Excellent students with high academic standing, who have clearly demonstrated the ability to do research at the doctoral level, may be considered for transfer to the PhD program. Recommendation by the student's supervisory committee is required.

  • Transfer applicants must successfully complete a reclassification (transfer) examination within 18 to 24 months of starting the program.

Completion Requirements

Students must complete any courses that were a condition of acceptance.

  • Coursework. Students must successfully complete a total of 3.5 full-course equivalents (FCEs) as follows:

    • BCH2020Y Seminar Course in Biochemistry Level 1

    • BCH2022Y Seminar Course in Biochemistry Level 2

    • BCH2101H Scientific Skills for Biochemists

    • 1.25 elective FCEs.

  • To be eligible to write the reclassification examination, students must:

    • complete BCH2101H

    • be concurrently registered in BCH2022Y

    • complete at least 0.25 elective FCE; after completing the reclassification examination, students must complete the remaining 1.0 elective FCE.

  • Submit a thesis and defend it at the Doctoral Final Oral Examination.

  • Normally, PhD students are expected to participate as full-time students and to maintain full-time status in their laboratories until thesis completion and final defence.

Mode of Delivery: In person
Program Length: 5 years full-time (typical registration sequence: Continuous)
Time Limit: 7 years full-time

 

PhD Program (Direct-Entry)

Minimum Admission Requirements

  • Direct entry is available to highly qualified BSc graduates who completed a Biochemistry specialist program or an appropriate undergraduate program in the life sciences from a recognized university, with a minimum A average in the final two years and relevant research experience.

  • Applicants are admitted under the General Regulations of the School of Graduate Studies. Applicants must also satisfy the Department of Biochemistry's additional admission requirements stated below.

  • Applicants must arrange for personal reference forms from three individuals familiar with their academic performance.

  • Applicants who obtained a degree outside Canada or the United States are generally required to have an MSc degree in biochemistry or in a closely related subject area with high academic standing.

  • Applicants whose primary language is not English and who graduated from a non-Canadian university where the language of instruction was not English must provide Test of English as a Foreign Language (TOEFL) and Test of Written English (TWE) scores:

    • paper-based TOEFL: minimum 580 score and 5 on the TWE

    • Internet-based TOEFL: minimum 93/120 score and 22/30 on the writing and speaking sections.

  • In the absence of TOEFL results, an International English Language Testing System (IELTS) score of at least 7.0 (Academic) with at least 6.5 for each component is also acceptable.

Completion Requirements

Students must complete any courses that were a condition of acceptance.

  • Coursework. Students must successfully complete a total of 3.5 full-course equivalents (FCEs) as follows:

    • BCH2020Y Seminar Course in Biochemistry Level 1

    • BCH2022Y Seminar Course in Biochemistry Level 2

    • BCH2101H Scientific Skills for Biochemists

    • 1.25 elective FCEs

  • Students must successfully complete a qualifying examination within 18 to 24 months of the program. To be eligible to write this qualifying examination, students must:

    • complete BCH2101H

    • be concurrently registered in BCH2020Y

    • complete at least 0.25 elective FCE; after completing the qualifying exam, students must complete the remaining 1.0 elective FCE.

  • Submit a thesis and defend it at the Doctoral Final Oral Examination.

  • Normally, PhD students are expected to participate as full-time students and to maintain full-time status in their laboratories until thesis completion and final defence.

Mode of Delivery: In person
Program Length: 5 years full-time (typical registration sequence: Continuous)
Time Limit: 7 years full-time

 

Biochemistry: Biochemistry MSc, PhD Courses

For course details and availability, consult the Biochemistry website.

Course CodeCourse Title
Seminar Course in Biochemistry Level 1
Seminar Course in Biochemistry Level 2
Focused Topics in Biochemistry
Protein Crystallography — Lectures
Protein Structure, Folding, and Design
Biochemistry of Inherited Disease
Current Topics in Molecular and Biochemical Toxicology
Molecular and Biochemical Basis of Toxicology
Fundamentals of Neuroscience: Cellular and Molecular

Modular Courses

Each modular course is worth 0.25 full-course equivalent (FCE).

Course CodeCourse Title
BCH2101HScientific Skills for Biochemists
BCH2102HBiomolecular Dynamics and Function
BCH2103HCurrent Topics in Prion Biology
BCH2104HThe Biochemistry of Translational Medicine
BCH2105HCystic Fibrosis: The Cause, The Treatment
BCH2106HMembrane Proteomics in Biomedical Research
BCH2107HIntroduction to Biomolecular Simulations
BCH2109HCurrent Topics in Therapeutic Antibodies
BCH2110HEukaryotic Signaling
BCH2111HPost-transcriptional Control of Gene Expression
BCH2112HFrom Chaperones to CRISPR-Cas: the Incredible Genius of Phages
BCH2113HAdvances in Precision Medicine
BCH2114HFrontiers in Drug Discovery
BCH2115HApplying Modern Evolutionary Thinking to Biochemistry, Cell, and Molecular Biology
BCH2116HElectron Paramagnetic Resonance Spectroscopy in Modern Life Sciences
BCH2119HAdvances in Epigenetics
BCH2120HStudies of Tissue Barriers: Regulation of Phenotype and Transport Across the Epithelium and Endothelium
BCH2121HLipid Metabolism in Health and Disease: Mechanisms of Diabetic Dyslipidemia in Obesity and Type 2 Diabetes
BCH2122HThe Use of High Content Screening in Biomolecular Medicine
BCH2123HProtein Structure Prediction and Homology Modelling
BCH2124HMolecular Chaperones and Cellular Protein Homeostasis
BCH2125HStructure and Dynamics of Biomacromolecules Using Solid State NMR Spectroscopy
BCH2126HSubcellular Social Networks: Inter-Organelle Contact Sites
BCH2127HAdvances in Optical Microscopy: From Single Molecules to Four-Dimensional Imaging
BCH2128HScientific Thinking and Practice
BCH2129HGenome Instability: Basic Science to Human Disease
BCH2130HCancer Biology
BCH2131HGenomics of Infectious Disease
BCH2132HModelling Human Diseases from Cells to Organoids
BCH2133HTyrosine Kinase Signaling
BCH2134HCytoskeletal Dynamics
BCH2135HMitochondria and Metabolism in Human Health and Disease
BCH2136HBiological Condensates
BCH2137HBug v. Host
BCH2138HAdvanced Electron Microscopy
BCH2139HIslet Biology I: Gene to Cell to Organ to Disease
BCH2140HIslet Biology II: Beyond Glucose Control: Molecular Targets, Diagnostics and Cutting-Edge Technologies
BCH2141HAdvanced Methods in Biomolecular Interactions
BCH2142HSpecial Topics A
BCH2143HSpecial Topics B
BCH2200HDesign Thinking for Scientists
BCH2201HProfessional Development
BCH2202HIntro Programming in R
BCH2203HIntro Programming in Python
BCH2204HAdvanced Programming in R
BCH2205HAdvanced Programming in Python
BCH2206HInterdisciplinary Science
BCH2207HCollaborative Science: Student Centered Interdisciplinary Studies