Laboratory Medicine and Pathobiology

LMP: Introduction

​​​​​​​​​​​​​​​​​​​​​​​​​Faculty Affiliation

Medicine

Degree Programs

Laboratory Medicine and Pathobiology

​​MSc
PhD

Combined Degree Programs

​​​MD / PhD

​​Collaborative Specializations

The following collaborative specializations are available to students in participating degree programs as listed below:

  1. Biomedical Engineering
    • Laboratory Medicine and Pathobiology, MSc, PhD
  2. Biomedical Toxicology
    • Laboratory Medicine and Pathobiology, MSc, PhD
  3. Cardiovascular Sciences
    • Laboratory Medicine and Pathobiology, MSc, PhD
  4. Developmental Biology
    • Laboratory Medicine and Pathobiology, MSc, PhD
  5. Genome Biology and Bioinformatics
    • Laboratory Medicine and Pathobiology, PhD
  6. Musculoskeletal Sciences
    • Laboratory Medicine and Pathobiology, MSc, PhD
  7. Neuroscience
    • Laboratory Medicine and Pathobiology, MSc, PhD
  8. Resuscitation Sciences
    • Laboratory Medicine and Pathobiology, MSc, PhD

Overview

As part of the Faculty of Medicine, the Department of Laboratory Medicine and Pathobiology offers unparalleled access to more than 350 expert faculty including basic scientists, pathobiologists, laboratory physicians, and scientists; outstanding case material; a stunning array of research opportunities; diverse training sites; engaging student-run organizations.  

Research Foci

Antimicrobial Resistance: Surveillance and Mechanisms
Bone and Connective Tissue Diseases including Disorders of Mineral Metabolism
Cancer Pathogenesis and Prevention Cardiovascular Disease
Cell-Matrix Interactions
Development: Cell Cycle, Differentiation, Signalling Diabetes
Endocrine and Neuroendocrine Disorders
Hematopathology and Transfusion Medicine
Immunopathology and Transplantation
Inflammatory Disorders
Lipid Disorders
Lymphatic Pathobiology
Microbial Pathogenesis
Molecular Biomarkers
Neurodegenerative Disorders
Proteomics and Bioinformatics
Protein Structure and Function
Toxicology
Translational Research
Vascular Cell Biology
Viral Diseases

For details, consult the departmental website.

Contact and Address

Admission

Web: www.lmp.utoronto.ca
Email: r.ponda@utoronto.ca
Telephone: (416) 978-2550
Fax: (416) 978-7361

Program

Web: www.lmp.utoronto.ca
Email: ferzeen.sammy@utoronto.ca
Telephone: (416) 978-2663​
Fax: (416) 978-7361

Department of Laboratory Medicine and Pathobiology
University of Toronto
Medical Sciences Building
Room 6209, 1 Ki​ng's College Circle
Toronto, Ontario M5S 1A8
Canada

LMP: Graduate Faculty

Full Members

Abdelhaleem, Mohamed - MSc, MBCHB, PhD
Adeli, Khosrow - DipChem, MSc, PhD
Alman, Benjamin - BSc, MD
Andrulis, Irene - BA, PhD
Asa, Sylvia - MD
Aubert, Isabelle - BSc, PhD
Bapat, Bharati - BSc, MSc, PhD
Barber, Dwayne - BSc, PhD
Bartlett, John M.S. - PhD
Bendeck, Michelle - BSc, PhD
Bergeron, Catherine - MD
Boggs, Joan - MSc, PhD
Bognar, Andrew - BSc, PhD
Boyd, Shelley - BM
Branch, Donald - BA, BSc, PhD
Bremner, Roderick Angus - BSc, PhD
Brown, Martha - BSc, MSc, PhD
Buchan, Alison - BSc, MASc, PhD
Cole, David - BSc, MD, PhD
Connelly, Philip - BA, PhD
Crowcroft, Natasha - BA, MA, MSc, MBBS, PhD
Cutz, Ernest - MD
Cybulsky, Myron - MD
Dabdoub, Alain - BSc
Delabie, Jan - MD, PhD
Dennis, James - PhD
Diamandis, Eleftherios - BSc, MD, PhD
Dirks, Peter - MD, PhD
Dittakavi, Sarma - BSc, MSc, PhD
Done, Susan - BA, MA, MBA, BCh, MB, PhD
Drucker, Daniel - MD
Elsholtz, Harry - BSc, MSc, PhD (Coordinator of Graduate Studies)
Fish, Jason - BSc, PhD
Gilbert, Richard - MBBS, PhD
Girardin, Stephen - BSc, PhD
Gotlieb, Avrum - BSc, MDCM
Grynpas, Marc - MSc, PhD
Hakem, Razqallah - PhD
Hamel, Paul - BSc, PhD
Harrison, Rene - BS, MS, PhD
Hawkins, Cynthia - MD, PhD
Hedley, David - MD
Hegele, Richard - MD (Chair and Graduate Chair)
Hinek, Aleksander - MD, PhD
Hu, Jim - BSc, PhD
Huang, Annie - MD
Husain, Mansoor - MB, MD
Hwang, David - BSc, MD, PhD
Irwin, David - BSc, PhD
Jamieson, Frances - MD
Jin, Tianru - PhD
Joshi-Sukhwal, Sadhna - BSc, MSc, PhD, DSc
Jothy, Serge - MSc, MD, PhD
Kain, Kevin - MD
Kamel-Reid, Suzanne - BA, MA, PhD
Kandel, Rita - MD
Kapoor, Mohit - BPHM, MSc, PhD
Keeley, Frederick - BSc, PhD
Khokha, Rama - BSc, MSc, PhD
Kingdom, John - DipCH, MB, MD
Laflamme, Michael - BS, MD, PhD
Lazarus, Alan - PhD
Lee, Jeffrey - BSc, PhD
Levy, Gary - BSc, MD
Lingwood, Clifford - BSc, PhD
Marsden, Philip - MD
Mazzulli, Tony - MD
McCulloch, Christopher - BSc, DDS, PhD
McGeer, Allison - BSc, MSc, MD
McKerlie, Colin - DVSM, DVM
McLaurin, Joanne - BSc, MSc, PhD
Mekhail, Karim - BSc, PhD
Mogridge, Jeremy - BSc, PhD
Ni, Heyu - MSc, MD, PhD
O'Brien, Catherine - BSc, MSc, DrMed, PhD
Ohh, Michael - BSc, PhD
Opas, Michal - MSc, PhD
Ostrowski, Mario - MD
Palaniyar, Nades - MSc, PhD
Post, Martin - PhD
Pritzker, Kenneth - BSc, MD
Prud'homme, Gerald - MD
Rajalakshmi, Srinivasan - BSc, MA, PhD
Rand, Margaret - BSc, PhD
Reis, Marciano - MD
Richardson, Susan - BSc, MDCM
Robertson, Janice - BSc, PhD
Rosenblum, Norman - MD
Rozakis-Adcock, Maria - BSc, PhD
Rutka, James - BSc, LMCC, MD, PhD
Schmitt-Ulms, Gerold - BSc, MSc, DrRerNat
Seth, Arun - MS, PhD
Shaw, Patricia - SB, MD
Sivak, Jeremy - PhD
Strauss, Bradley - MD
Swallow, Carol - BA, MD, PhD
Taylor, Michael - BSc, DrMed, PhD
Templeton, Douglas - BSc, MD, PhD
Tenenbaum, Howard - DipPerio, DDS, PhD
Thorner, Paul - MD, DPhil
Tron, Victor - MD
Tsao, Ming-Sound - BSc, MD
van der Kwast, Theodorus - MD, PhD
Wang, Chen - MD, PhD
Wilson, Gregory - MSc, MD
Wong, Pui-Yuen - BSc, PhD
Yang, Burton - BSc, MSc, PhD
Yeger, Herman - BSc, MScPhm, PhD
Yousef, George - MSc, MD, PhD
Yucel, Yeni - MD
Zacksenhaus, Eldad - PhD
Zhang, Li - MSc, MD, PhD

Members Emeriti

Johnston, Miles - BSc, PhD
Marks, Alexander - MD, PhD
Minta, Joe - BSc, MBA, MSc, PhD
Shek, Pang - BSc, MSc, PhD

Associate Members

Aldape, Kenneth - BASc, MD
Allen, Vanessa G - BA, MD
Berman, Hal K. - MD, PhD
Blasutig, Ivan M. - BSc, PhD
Broukhanski, Gueorgui - MSc, PhD
Callum, Jeannie - BA, MD
Chandran, Vinod - MBBS, PhD
Chang, Hong - MSc, MD, PhD
Charames, George - BS, MS, PhD
Clarke, Blaise - MBCHB
Coburn, Bryan - BSc, DrMed
Colantonio, David - BSc, MSc, PhD
Das, Sunit - DrMed
Diamandis, Phedias - BS, MD, PhD
Drabovich, Andrei - MS, PhD
Epelman, Slava - MD, DrMed
Fittipaldi, Nahuel Vicente - BS, MS, PhD
Gandhi, Rajiv - BSc, MSc, MD
Gubbay, Jonathan B. - BSc, MSc, MBBS
Hazrati, Lili-Naz - BSc, MSc, MD, PhD
Hurtig, Mark - MSc, DVM
Keating, Sarah - MSc, MD
Kulasingam, Vathany - BSc, PhD
Kus, Julianne - BS, MS, PhD
Lerner-Ellis, Jordan - BS, PhD
Li, Ren-Ke - MHSc, MSc, MD, PhD
Licht, Christoph - MD
MacParland, Sonya - BS, MS, PhD
Magalhaes, Marco - MSc, BDS, PhD
Mallo, Gustavo - MSc, PhD
Melano, Roberto - MSc, PhD
Mete, Ozgur - MD
Moraes, Theo - MD
Munoz, David - MSc, MD
Ng, Dominic - MD
Pasic, Maria - BS, PhD
Patel, Samir - MSc, PhD
Pollanen, Michael - BSc, MD, PhD
Poutanen, Susan - MPH, MD
Riddell, Robert - LMCC, LRCP, MBBS
Robbins, Clinton Shane - BS, PhD
Romaschin, Alexander - DipChem, BSc, PhD
Rouzbahman, Marjan - MD
Shlien, Adam - BS, PhD
Sholzberg, Michelle - BSc, DrMed
Simor, Andrew - MD
So, Joyce - MD, PhD
Somers, Gino - MBBS, BMedSc, PhD
Spears, Melanie - BS, PhD
Stockley, Tracy - BSc, PhD
Sung, Hoon-Ki - MS, MD, PhD
Tein, Ingrid - MD
Vasconcelos, Sara
Waters, Valerie - MD
Winer, Daniel - BS, MD
Zai, Clement - BSc, MSc, PhD

LMP: Laboratory Medicine and Pathobiology MSc

​Master of Science​

Program Description

The MSc program emphasizes the development of analytical technologies, the application of basic research techniques in biochemistry, cell biology, clinical biochemistry, experimental pathology, genetics, immunology, and molecular biology to the study of mechanisms of cell and tissue injury and the pathogenesis of disease. The program also emphasizes the nature, mechanisms, therapy, and prevention of microbial diseases in humans, as well as the processes by which pathogenic microbes are spread.

 

Minimum Admission Requirements

  • Applicants are admitted under the General Regulations of the School of Graduate Studies. Applicants must also satisfy the Department of Laboratory Medicine and Pathobiology's additional admission requirements stated below.

  • Applicants must have completed, or be about to complete, one of the following:

    • ​​Pathobiology Specialist program

    • an appropriate bachelor's degree in life sciences from a recognized university

    • professional degree (e.g., MD, DDS, DVM, or equivalent).

  • A minimum A- average over the final two years of undergraduate study.

  • Two strong letters of recommendation from faculty members familiar with the applicant's academic work. Departmental appraisal forms must be used.

  • Detailed curriculum vitae (CV).

  • Statement of intent (approximately 250 words).

  • Research experience evidenced by publications, abstracts, or presentations is an asset.

  • Successful applicants are selected by the departmental admissions committee on the basis of academic excellence and an interview with a member of the departmental graduate faculty.

Admission is finalized when a graduate faculty member agrees to supervise the student's research and guarantees a full stipend for the student.

Program Requirements

  • Coursework. Students must complete 1.5 full-course equivalents (FCEs) as follows:

    • Students who have not previously completed LMP 1404H Molecular and Cellular Mechanisms of Disease (0.5 FCE), or an approved equivalent, will be required to take this course in Year 1. Students exempted from LMP 1404H will take a departmental half course (0.5 FCE) as a substitute. The student's advisory committee may recommend additional courses.

    • Students must enrol and participate in a credit/no-credit course, LMP 1001Y Graduate Seminars in Laboratory Medicine and Pathobiology (1.0 FCE), which must be taken throughout the program. Students must present at least once in LMP 1001Y prior to defending their thesis.

    • Students must attend the LMP Monday Seminar Series, a departmental guest lecture series that immediately follows the student seminar course LMP 1001Y.

  • Completion of a thesis under the direction of the student's supervisor, assisted by the advisory committee.

  • Within 12 to 18 months of entry, students will be advised by their committee to do one of the following:

    • write and orally defend a thesis on research completed,

    • transfer to the PhD program, or

    • withdraw from the MSc program.

  • The research content of the MSc thesis is expected to generate the equivalent of one paper published in a peer-reviewed scientific journal.

  • Residence. Students must be on campus and participating for the duration of their registration in the program.

Program Length

5 sessions (2 years) full-time (typical registration sequence: F/W/S/F/W)

Time Limit

3 years full-time

LMP: Laboratory Medicine and Pathobiology PhD

​Doctor of Philosophy​

Program Description

The PhD program emphasizes the development of analytical technologies, the application of basic research techniques in biochemistry, cell biology, clinical biochemistry, experimental pathology, genetics, immunology, and molecular biology to the study of mechanisms of cell and tissue injury and the pathogenesis of disease. The program also emphasizes the nature, mechanisms, therapy, and prevention of microbial diseases in humans, as well as the processes by which pathogenic microbes are spread.

Applicants may enter the PhD program via one of three routes: 1) following completion of an MSc degree; 2) transfer from the University of Toronto MSc program; or 3) direct entry following completion of a BSc degree.

A limited number of selected students may enter the combined degree program in Medicine, Doctor of /Doctor of Philosophy (MD/PhD) subject to admission into both the departmental PhD program and the MD program.

 

Minimum Admission Requirements

  • Applicants are admitted under the General Regulations of the School of Graduate Studies. Applicants must also satisfy the Department of Laboratory Medicine and Pathobiology's additional admission requirements stated below.

  • Two routes of entry are available:

    1. Track A:

      • ​​​​​​​​​​​​​​​​​​​​​​​Direct entry is available for highly qualified BSc graduates having completed the Pathobiology Specialist program or an appropriate undergraduate program in the life sciences from a recognized university with a minimum A average in the final two years and relevant research experience. These students are encouraged to apply directly to the PhD program.

      • Excellent students with high academic standing (normally minimum A- average on MSc courses) who have clearly demonstrated the ability to do research at the doctoral level may be considered for transfer to the PhD program. Recommendation of the advisory committee is required. Transfer to the PhD program is based on the student’s performance at an assessment examination, which is held 12 to 18 months after the start of the MSc program. The student’s supervisor will schedule the assessment examination. The examining committee consists of at least si​x members of the graduate faculty:

        • ​the Graduate Coordinator (or a representative from the graduate faculty of the department) who chairs the examination committee,

        • the student's advisory committee, and

        • two other graduate faculty members, one of whom is a member from another graduate department.

    2. Track B: ​MSc graduates and applicants with an MD, DDS, DVM (or equivalent) degree are eligible for t​he PhD program. An A- average or higher is required in graduate courses or in an appropriate BSc program if there were no course requirements in the MSc program.

  • Research experience evidenced by peer-reviewed publications, abstracts, or presentations is normally required.

  • Three strong letters of recommendation from faculty members familiar with the applicant's academic work. Departmental appraisal forms must be used. Normally, one of the referees should be the applicant's research supervisor.

  • A detailed curriculum vitae (CV).

  • Statement of intent (approximately 250 words).

  • Applicants are selected by the departmental admissions committee on the basis of academic excellence and successful performance at an interview with a member of the departmental graduate faculty. Admission to the program is finalized when a graduate faculty member agrees to supervise the student's research and guarantees a full stipend for the student.

  • Excellent students with high academic standing (normally minimum A- average on MSc courses) who have clearly demonstrated the ability to do research at the doctoral level may be considered for transfer to the PhD program. Recommendation of the advisory committee is required. Transfer to the PhD program is based on the student's performance at an assessment examination, which is held 12 to 18 months after the start of the MSc program. The student's supervisor will schedule the assessment examination. The examining committee consists of at least six members of the graduate faculty:

    • ​​​​the Graduate Coordinator (or a representative from the graduate faculty of the department) who chairs the examination committee,

    • the student's advisory committee, and

    • two other graduate faculty members, one of whom is a member from another graduate department.

  • A limited number of selected students may enter the MD/PhD program subject to admission into both the departmental PhD program and the MD program.

Program Requirements

  • Coursework. Students must complete 3.0 full-course equivalents (FCEs) as follows: 

    • Students must enrol and participate in a credit/no-credit course, LMP 1001Y Graduate Seminars in Laboratory Medicine and Pathobiology (1.0 FCE), which must be taken throughout the program. Students must present at least twice in LMP 1001Y prior to defending their thesis.

    • Students must attend the LMP Monday Seminar Series, a weekly departmental guest lecture series that immediately follows the student seminar course LMP 1001Y.

    • Students who have not previously completed LMP 1404H Molecular and Cellular Mechanisms of Disease (0.5 FCE) or an approved equivalent are required to take this course in Year 1 of their PhD program. The student's advisory committee may recommend additional courses. Students exempted from LMP 1404H take an approved departmental half course (0.5 FCE) as a substitute.

    • Three half-course equivalents (1.5 FCEs), of which at least one half course is from Laboratory Medicine and Pathobiology. Exception: students having completed the undergraduate Pathobiology Specialist Program (or equivalent) are required to take only two additional half courses (0.5 FCe).

    • Coursework should be completed in the first two years of the program, the continuing seminar course excepted. The latter half of the program is focused on research.

    • Students who take additional graduate courses during the MSc program and who continue their graduate studies in the PhD program may request a transfer credit up to one full-course towards doctoral course requirements. Credit for courses must be approved by the Graduate Coordinator; certain restrictions may apply.

  • Prior to the start of Year 3, the advisory committee may recommend that a PhD student transfer to the MSc program. The student may also request the transfer.

  • The PhD thesis is completed under the direction of the candidate's supervisor, assisted by the advisory committee. The candidate normally defends the thesis before a departmental committee, and subsequently before a committee approved by the School of Graduate Studies. Candidates may, with the recommendation of their advisory committee, request a waiver of the departmental defence, subject to approval by the Graduate Coordinator.

  • The PhD thesis must demonstrate a substantial contribution to laboratory medicine and pathobiology, involving a systematic investigation of disease-related hypotheses. The emphasis is on quality of the science and its presentation. The PhD thesis is normally expected to yield the equivalent of three publications in refereed scientific journals.

  • Residence. Students must be on campus and participating for the duration of their registration in the program.

Program Length

4 years full-time; 5 years transfer-from-master's; 5 years direct-entry

Time Limit

6 years full-time; 7 years transfer-from-master's; 7 years direct-entry

LMP: Laboratory Medicine and Pathobiology MSc, PhD Courses

Not all courses are offered every year. Please check the departmental website for course availability.

​LMP 1001Y
Graduate Seminars in ​​Laboratory Medicine and Pathobiology (Credit/No Credit) (mandatory for all MSc and PhD students in the Department of Laboratory Medicine and Pathobiology)
​LMP 1005Y
General and Special Pathology (for Oral Pathology Residents only)​
​LMP 1006H
Cellular Imaging in Pathobiology​
​LMP 1013H
Neoplasia​​​
​LMP 1017H
​Tissue Injury, Repair, and Regeneration
​LMP 1019H
Research Techniques in Molecular Biology and Pathobiology​
​LMP 1020H
Inflammation, Immunity, and Immunopathology of Atherosclerosis​
​LMP 1404H
​Molecular and Cellular Mechanisms of Disease (mandatory for all MSc and PhD students in the Department of Laboratory Medicine and Pathobiology)
​LMP 1407H
​Introductory Biostatistics and Clinical Investigation
​LMP 1503H
​Signal Transduction Pathways in Normal and Diseased Tissues
​LMP 1504H
​Cell and Molecular Biology of Cardiovascular Diseases
​LMP 1505H
​Analytical Clinical Biochemistry: Basic Principles
​LMP 1510H
​Molecular Biology Techniques
​​LMP 1520​H
​Translational Research in Pathobiology
​LMP 1525H
​The Role of Genomics in the Era of Personalized Medicine
​LMP 1530H
​Next Generation Genomics in Clinical Medicine
​LMP 1535H
​Mass Spectrometry, Proteomics, and Their Clinical Applications
​LMP 2115H
​Selected Topics in Medical Microbiology
​LMP 2120H
​Molecular Clinical Microbiology and Infectious Diseases
​LMP 2222H
​Neurodegenerative Disease—Mechanisms, Models, and Methods
​RST 9999Y
​​Research Project (Credit/No Credit)